Hepatobiliary and Pancreatic Carcinogenesis in the Hamster


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Kommentar verfassen. This unique book explains the methods for the successful induction of hepatobiliary and pancreatic tumors in hamsters. Techniques for preparing animal models, the histopathological characteristics of the induced tumors, and chemoprevention are also covered.

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Histogenesis of pancreatic carcinogenesis in the hamster: ultrastructural evidence.

Versandkostenfrei Bestellungen mit diesem Artikel sind versandkostenfrei! The mechanism of carcinogenesis as well as the growth and spread of these tumors is still poorly understood, making the development of rational tre- ment strategies difficult. In order to improve the clinical results achieved by sur- cal or other medical treatment of such malignant tumors, the establishment of an experimental animal model is critical. For this purpose, attempts were made to induce carcinoma experimentally in the biliary tree and finally an animal model using the hamster was established in at our laboratory.

Because the tumor in this model mimicked the characteristics of human tumors, a series of experimental investigations were conducted to clarify the pathological characteristics of biliary carcinoma, the genetic alterations during biliary carcinogenesis, and the relationship between biliary inflammation and c- cinogenesis.

The chemopreventive effects on the occurrence of biliary carcinoma were also successfully examined.

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The effect of partial pancreatectomy.

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Hepatobiliary and Pancreatic Carcinogenesis in the Hamster Hepatobiliary and Pancreatic Carcinogenesis in the Hamster
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